Up-regulation of tumor necrosis factor-alpha in spinal cord contributes to vincristine-induced mechanical allodynia in mice
N Kiguchi, T Maeda, Y Kobayashi, S Kishioka - Neuroscience letters, 2008 - Elsevier
… allodynia is still unclear. In this study, we focused on tumor necrosis factor-alpha (TNF-α)
in spinal cord, and investigated the role of TNF-α in VCR-induced allodynia in mice. VCR (0.1 …
in spinal cord, and investigated the role of TNF-α in VCR-induced allodynia in mice. VCR (0.1 …
Methylcobalamin ameliorates neuropathic pain induced by vincristine in rats: effect on loss of peripheral nerve fibers and imbalance of cytokines in the spinal dorsal …
J Xu, W Wang, XX Zhong, YW Feng, XH Wei… - Molecular …, 2016 - journals.sagepub.com
… We found that vincristine-induced mechanical allodynia and … Production of tumor necrosis
factor α was also decreased … -α in the spinal cord contribute to vincristine-induced neuropathic …
factor α was also decreased … -α in the spinal cord contribute to vincristine-induced neuropathic …
Oral Application of Magnesium-l-Threonate Attenuates Vincristine-induced Allodynia and Hyperalgesia by Normalization of Tumor Necrosis Factor-α/Nuclear Factor …
T Xu, D Li, X Zhou, HD Ouyang, LJ Zhou, H Zhou… - …, 2017 - pubs.asahq.org
… In the spinal cord, TNF-α was expressed virtually in all dorsal … vincristine-induced NR2B
up-regulation in the spinal dorsal horn, which may contribute to its inhibitory effect on allodynia …
up-regulation in the spinal dorsal horn, which may contribute to its inhibitory effect on allodynia …
Exogenous induction of HO-1 alleviates vincristine-induced neuropathic pain by reducing spinal glial activation in mice
Y Shen, ZJ Zhang, MD Zhu, BC Jiang, T Yang… - Neurobiology of …, 2015 - Elsevier
… contribution of HO-1 in the modulation of vincristine-induced … of vincristine induced
persistent mechanical allodynia and … in the spinal cord and attenuated vincristine-induced pain. …
persistent mechanical allodynia and … in the spinal cord and attenuated vincristine-induced pain. …
[HTML][HTML] Wnt/β-catenin signaling contributes to vincristine-induced neuropathic pain
HU Chuanyin, Z Yun-Tao, CUI Yan-Bing… - Physiological …, 2020 - ncbi.nlm.nih.gov
… In the fourth series of experiments, the spinal cords of mice … signaling in the spinal cord
contributed to the maintenance of … ERK1/2 and the established mechanical allodynia, our results …
contributed to the maintenance of … ERK1/2 and the established mechanical allodynia, our results …
Spinal astrocytic activation contributes to mechanical allodynia in a rat chemotherapy-induced neuropathic pain model
XT Ji, NS Qian, T Zhang, JM Li, XK Li, P Wang… - PloS one, 2013 - journals.plos.org
… spinal cord and the influence of different glial inhibitors on mechanical allodynia in vincristine
treated rats… astrocytic specific inhibitor) in a vincristine induced CNP rat model. Furthermore…
treated rats… astrocytic specific inhibitor) in a vincristine induced CNP rat model. Furthermore…
Levo-corydalmine alleviates vincristine-induced neuropathic pain in mice by inhibiting an NF-kappa B-dependent CXCL1/CXCR2 signaling pathway
L Zhou, Y Hu, C Li, Y Yan, L Ao, B Yu, W Fang, J Liu… - …, 2018 - Elsevier
… and how CXCL1 contributes to vincristine-induced pain and … NFκB expression in the spinal
cords of mice treated with l-… of CXCL1, the up-regulation of neuronal CXCR2 expression …
cords of mice treated with l-… of CXCL1, the up-regulation of neuronal CXCR2 expression …
The critical role of invading peripheral macrophage-derived interleukin-6 in vincristine-induced mechanical allodynia in mice
… IL-6 and tumor necrosis factor-alpha are the cytokines, … spinal cord release IL-6 in
vincristine-treated mice, we speculate that the contribution of peripheral IL-6 is more than that of …
vincristine-treated mice, we speculate that the contribution of peripheral IL-6 is more than that of …
Minocycline prevents the development of mechanical allodynia in mouse models of vincristine-induced peripheral neuropathy
… of neurons in the spinal cord leading to neuronal hyper-… contributes to the development
of VIPN and suggests that Tlr4 may be a novel target for the treatment of vincristine-induced …
of VIPN and suggests that Tlr4 may be a novel target for the treatment of vincristine-induced …
Involvement of inflammatory mediators in neuropathic pain caused by vincristine
N Kiguchi, T Maeda, Y Kobayashi, F Saika… - International review of …, 2009 - Elsevier
… in vincristine‐induced neuropathic pain in this review. … and astrocytes in the spinal cord were
demonstrated after long‐term … Astrocytes are therefore important cells that contribute to the …
demonstrated after long‐term … Astrocytes are therefore important cells that contribute to the …